Eosinophilia and Vasculitis

1. Classic Presentation of EGPA: Chung-Strauss (not nazis) Vasculitis is classically presents in an ANCA-positive patients with a clinical syndrome consistent with vasculitis on a background of asthma (nearly 100% of the time) and peripheral eosinophilia (see differential dx for eosinophilia above, Immunol Allergy Clin North Am. 2015 Aug;35(3):387-402.) and is treated with systemic steroids, plus/minus additional immunomodulators such as azathioprine, cyclophosphamide, and rituximab.

2.  A fantastic journal to pick up if you're curious about the ways in which eosinophils manifest in the world of internal medicine would be the following special issue of Immunology and Allergy Clinics of North America, which focuses on eosinophilic diseases: Immunology and Allergy Clinics of North America. Volume 35, Issue 3, Pages 387-598 (August 2015) Eosinophil-Associated Disorders