Block 4 - Meta analysis & medical reversal
Look at the landmark 2001 Leuven/ Van den Berghe Surgical trial showing mortality benefit in intensive ICU glycemic control vs modern systematic review and meta analysis from CHEST.
Appraising a systematic review - PDF
JAMA user guide to systematic reviews - PDF
Block 5 - Therapy
Discuss the recent PARADIGM-HF trial comparing angiotensin receptor-neprilysin inhibitor sacubitril-valsartan with enalapril in patients with HFrEF.
Drafting a letter to the editor or viewpoint on a current paper. TBA.
Block 8 - Bias
Discussion of bias in the literature